Buy Turinabol Hilma Biocare 100tabs 10 mg/tab in Europe. Turinabol 10 is a 17-alpha alkylated anabolic steroid for oral use. It promotes anabolism through androgen receptor activity and is strongly anabolic and moderately androgenic. When taken in clinical doses, it produces potent increases in strength and moderate increases in muscle mass. In short term clinical trials, it has been well tolerated in healthy male subjects during 6 weeks of treatment.
Strength: 10 mg
Molecular Formula: C20H27CLO2
Molecular Weight: 334.88018 g/mol
Active Ingredient: Chlorodehydromethyltestosterone
CAS number: 2446-23-3
Dosage Form: Tablet
Route: Oral
Market Status: Prescription
Company: Hilma Biocare
CLINICAL PHARMACOLOGY
Anabolic steroids are synthetic derivatives of testosterone. Certain clinical effects and adverse reactions demonstrate the androgenic properties of these drugs. Anabolic steroids suppress the gonadotropic functions of the pituitary and may exert a direct effect upon the testes. During exogenous administration of anabolic androgens, endogenous testosterone release is inhibited through inhibition of pituitary luteinizing hormone (LH). At larger doses,
spermatogenesis may be suppressed through feedback inhibition of pituitary follicle stimulating hormone (FSH) In a single dose pharmacokinetic study of Chlorodehydromethyltestosterone, 10mg administered orally to healthy males reached maximum serum levels in 3 hours It is subject to first pass hepatic deactivation rapidly with a strong dominance of bioactive metabolites over the parent drug within a few hours. Prior to reaching serum orally dosed subjects exhibited significant variations in serum absorption levels linked to variations in enterohepatic circulation as demonstrated by radiographic label tracing. In a study involving IV administration of Turnibol 10, the terminal half-life of the parent molecule was found to be 16-hours. Given the lack of consensus on the bioactivity of its metabolites and
the predominance of metabolites over the parent drug after oral administration a clinically useful biological half-life remains unclear. Turnibol has maxim demonstrated an affinity for SHBG introducing competition for testosterone binding, thereby yielding increased plasma levels of unbound testosterone. Buy Turinabol Hilma Biocare 100tabs 10 mg/tab in Europe.
INDICATION AND USAGE
Turnibol 10 is indicated as alternate or adjunctive therapy in patients for the promotion of
weight gain following weight loss and/or muscular atrophy associated with extensive surgery,
chronic infections, Jong term hospitalization, or severe trauma. Turnibol 10 is indicated to
compensate for protein catabolism consequent to corticosteroid therapy.The physician and
patient must consider the risks of therapy versus the potential benefits.
CONTRAINDICATIONS
Patients with known hypersensitivity to any ingredients in this product. Patients with known
or suspected carcinomas of the breast, testis, or prostate. Patients with severe heart
disease, liver disease, or kidney disease or with a history of epilepsy. Products containing
androgens should not be used in women as they may cause virilization and fetal harm.
Patients with nephrosis or the nephrotic phase of nephritis, ed Patients with hypercalcemia.
sleM Patients with pre-existing cardiac, renal, and/or hepatic disease. Buy Turinabol Hilma Biocare 100tabs 10 mg/tab in Europe.
PRECAUTIONS
Elevated liver enzymes and in rare cases hepatic liver dysfunction may occur. Periodic liver
function tests should be conducted given the association of 17-alpha- alkylated androgens
with hepatotoxicity and treatment discontinued if the patient presents with signs of
hepatotoxicity or jaundicing. Edema may be increased in patients on concurrent adrenal
cortical steroid or ACTH therapy. Androgenic anabolic steroids have been associated with
changes in serum lipids, generally with decreases in high-density lipoprotein (HDL)
concentration and increases in low-density lipoprotein (LDL) concentration, a profile known
to be associated with increased risk of atherosclerosis and associated risk of coronary artery
disease. Thus caution should be used when administering these drugs to patients with a
history of myocardial infarction or coronary artery disease. Anabolic steroids may reduce
clotting factors II, V, VII, and X, and may increase prothrombin time (PT). Patients should be
instructed to report any use of warfarin or other oral anticoagulant therapy and any irregular
bleeding. Male patients receiving androgenic anabolic steroid therapy may be at an
increased risk of prostate hypertrophy. Buy Turinabol Hilma Biocare 100tabs 10 mg/tab in Europe.
DRUG INTERACTIONS
Oral hypoglycemic agents: may inhibit the metabolism of these agents which may require
adjustment of dosage. Anticoagulants: Patients on anticoagulants should be carefully
monitored during anabolic steroid therapy as anabolic steroids may increase sensitivity to
oral anticoagulants. Patients should be monitored regularly during anabolic steroid therapy,
particularly during initiation and termination of therapy.
Diabetics: androgens may alter the metabolism of oral hypoglycemic agents or may change
insulin sensitivity inpatients with diabetes mellitus which may require adjustment of dosage
of insulin and other hypoglycemic drugs.
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